Kashamu represented Ogun east in the eighth senate.
He had a brush with the law over allegations of drug dealing while he was in the US.
In 2015, there was a stand-off at his residence after operatives of the National Drug Law Enforcement Agency (NDLEA) attempted to arrest him for extradition to the US.
He challenged the attempt to extradite in court until his death.
He was 62 years old.
Kashamu is the latest casualty in the growing list of prominent figures killed by COVID-19.